The heat used during HIPEC not only helps in killing cancer cells but also improves the absorption of the chemotherapy drugs. This localized delivery allows for a much higher dose of medication to be administered compared to traditional systemic chemotherapy, which is distributed throughout the entire body. The direct application ensures that the cancer cells receive a potent dose, increasing the likelihood of effective treatment.

Some studies suggest that HIPEC can improve overall survival rates for certain patients, especially those with an advanced abdominal cancers that has spread, particularly ovarian cancer and peritoneal carcinomatosis. This offers hope to patients who may have fewer treatment options. The combination of surgery and heated chemotherapy has been linked to prolonged survival.

HIPEC delivers chemotherapy directly to the area where the cancer is located. This means that the treatment goes straight to the source, which can be more effective than standard chemotherapy that circulates throughout the entire body thus minimises the exposure of healthy tissues to the toxic effects of the drugs.

Since HIPEC targets only the abdominal wall area, fewer systemic side effects compared to traditional chemotherapy.

The combination of heat and chemotherapy enhances the susceptibility of cancer cells to the drugs. Cancer cells are generally more sensitive to elevated temperatures, which means that the heated chemotherapy can be more effective in killing these cells. This synergistic effect can lead to better treatment outcomes, particularly for tumours that are difficult to treat with standard chemotherapy.

HIPEC used in conjunction with surgery to remove visible tumours. This flexibility allows for a more personalized treatment plan that can address the unique characteristics of each patient’s cancer as well as help eliminate any remaining cancer cells, potentially reducing the chances of recurrence.