镥-177 PSMA治疗用于治疗晚期前列腺癌病患，特别是那些对标准系统治疗产生耐药性的病患。扩散到身体其他部位的前列腺癌细胞在其表面表达一种独特的物质，称为前列腺特异性膜抗原（PSMA）。
标记于PSMA的镥-177将特异性地附在PSMA表达高的细胞上，好让高剂量的标靶放射治疗传递于细胞的同时避免对周遭的健康正常组织造成伤害。
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