There are certain women who get endometrial cancer who have no established risk factors. It is impossible to determine which risk factor, if any, contributed to the development of endometrial cancer in a woman who already had one or more of them.
The likelihood of getting endometrial cancer is influenced by numerous factors, such as:
- Being overweight/ obese/ high percentage of body fat
- Tamoxifen, oestrogen (only hormone replacement therapy) after menopause, polycystic ovarian syndrome (PCOS) and nulliparous (never given birth)
- Increasing age
- Diabetes type 2
- Family history: if there are near relatives who have colorectal or endometrial cancer or ovarian cancer (Lynch syndrome)
- Having previously had endometrial hyperplasia or ovarian cancer