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IORT (Brain Tumour Treatment)

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Redefining Brain Tumour Care

IORT is a targeted radiation therapy, delivered directly to the site where the tumour is resected during the surgery. The aim of IORT treatment is to deliver precise dose of radiation to the intended area for better treatment outcome, while minimising unnecessary damage to normal tissues. Multiple studies show clear evidence of how IORT is more effective in preventing future recurrences.

IORT utilises a miniaturised X-ray source to deliver a complete course of targeted radiation directly within the tumour cavity, where cancer cells are most likely to recur, meticulously destroying cancer cells while minimising the risk of damage to neighbouring healthy tissue.

IORT has been used to treat brain cancers such as Glioblastoma multiforme (GBM) and brain metastases. It is frequently used in conjunction with other treatments such as surgery, chemotherapy, and external beam radiation therapy.

According to Globocan 2020, annually, almost 837,000 cases of brain and nervous system tumours are detected worldwide. Glioblastoma (GBM) is the most frequent and aggressive type of malignant primary brain tumour, with a 10- to 12-month median survival.

Surgical excision of brain tumours is usually followed by radiation therapy or chemotherapy. When combined with standard radiation therapy, IORT is a treatment option that may provide better outcomes for patients with reduced side effects.

IORT may allow clinically eligible patients to possibly replace weeks of post-operative external beam radiation therapy (EBRT) with a single fraction of radiation for the treatment of certain forms of brain tumours.

According to Globocan 2020, annually, almost 837,000 cases of brain and nervous system tumours are detected worldwide. Glioblastoma (GBM) is the most frequent and aggressive type of malignant primary brain tumour, with a 10- to 12-month median survival.

Surgical excision of brain tumours is usually followed by radiation therapy or chemotherapy. When combined with standard radiation therapy, IORT is a treatment option that may provide better outcomes for patients with reduced side effects.

IORT may allow clinically eligible patients to possibly replace weeks of post-operative external beam radiation therapy (EBRT) with a single fraction of radiation for the treatment of certain forms of brain tumours.

Benefits of IORT for brain tumour

Improved precision

One of the most significant advantages of IORT is that it enables for more accurate tumour site targeting. This can help to lessen the likelihood of adverse outcomes while minimising damage to healthy adjacent brain tissue.

Reduced radiation exposure to surrounding normal tissues

Damage to healthy tissues surrounding the tumour, which might result in neurological impairments.

Reduced delay in radiation treatment

IORT is delivered to patients during surgery, hence, reducing the gap between surgery and the start of radiation therapy.

Improved local control

IORT could potentially be able to improve local tumour control, lowering the chance of recurrence.

Is IORT suitable for everyone with brain tumour?

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IORT for brain tumours is a highly specialised treatment option. It may not be suitable for all patients or all types of brain tumours. The decision to undergo IORT should be made in consultation with a multidisciplinary team of healthcare professionals, including neurosurgeons, radiation oncologists, and other specialists, who will carefully evaluate each individual case and recommend the most appropriate treatment approach.

Note: As with any medical procedure, it is critical to consult with your healthcare physician about the potential risks and benefits as well as to evaluate the appropriateness of IORT in the patient’s case and recommend the best treatment plan.
If you believe that IORT is the best treatment for you or a loved one, contact us today to know more. At Beacon Hospital, we have dedicated team of trained neuro surgeons and oncologist that can be consulted to determine if you are eligible for the treatment.

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