When a plasma cell undergoes a mutation, myeloma develops. B lymphocytes, or B cells, are a subset of white blood cells that reside in the bone marrow and are the source of plasma cells. As a component of the immune system, healthy plasma cells produce “antibodies,” which are proteins that aid in the battle against infection.

The myeloma cell, a mutant kind of plasma cell, spreads and will continue to grow in the bone marrow if left untreated. In the bone marrow, they displace the normal stem cells and healthy plasma cells that produce platelets, red blood cells, and white blood cells. If the malignant cells are not treated, they may:

• If healthy white blood cells are overpopulated, the immune system is unable to properly fight infection.
• Release a lot of protein into the urine and blood, which might harm the kidneys.
• Build up in the bone weakens it and can result in fractures and bone pain.