Glioblastoma Cancer

The exact causes of glioblastoma remain largely unknown, but several risk factors have been identified that may increase the likelihood of developing this aggressive brain tumour.

• Prior Radiation Exposure: History of radiation therapy to the head.
• Family History: Although most glioblastoma patients do not have a family history of the
  disease, a small percentage may have genetic predispositions that increase their risk.
• Genetic mutations: Genetic disorders that cause tumours, such as Turcot syndrome, Li-
  Fraumeni syndrome, and neurofibromatosis.
• Environmental Factors: Exposure to certain chemicals and carcinogens. For instances,
  pesticides, petroleum, synthetic rubber, and vinyl chloride.

Glioblastoma is an aggressive brain tumour that can present a variety of symptoms depending on its location and growth rate. Here are some of the most common signs and symptoms associated with glioblastoma:

• Headaches is often the first noticeable symptom which can differ from typical headaches and tend to become more frequent and severe over time, often worsening in the morning and may not respond to over-the-counter pain medications.
• Cognitive changes including memory loss, confusion, and difficulty concentrating which
  can significantly affect daily living.
• Seizures because of the tumor's impact on brain function that can vary in type and
  severity.
• Visual or sensory changes such as numbness or tingling in certain body parts.
• Nausea and vomiting which may be worse in the morning due to the tumour’s increased
  intracranial pressure.
• Motor Weakness which includes difficulty with coordination and balance, also can be
  indicative of the tumour’s location in the brain.
• Personality and mood changes as the tumour affects different areas of the brain.